Check our more Liothyronine (T3) for sale: 1) Liothyronine (T3) 100mcg (50 pills) by Maxtreme – 56$ 2) Liothyronine (T3) 25mcg (50 pills) Maxtreme – 31$ 3) Liothyronine (T3) 25mcg (30 pills) Alpha Pharma – 13$ The problem of instability of T3 The first thing to consider about dosing of T3 is that the drug itself has poor stability, resulting in loss of potency with time even with some tabletted pharmaceutical products. Liquid preparations are even more prone to loss of potency. Dosings given below refer to fully potent T3, as found with US-made or European pharmaceutical products still within expiration date. In many instances, other T3 products will contain less or even much less T3 than the label may indicate. For this reason, I recommend seeking out genuine pharmaceutical T3, preferably of American or European origin. Otherwise, dosing can be uncertain or deceptive. For example, a person might find “150 mcg” per day to be an appropriate dose for him when using a low-potency product, but an extreme overdose when using a full-potency product. In simple terms, when you use synthetic T3, you are increasing your overall thyroid hormone levels, which causes metabolism to speed up. Unfortunately, when you do this, your body will stop producing T3 naturally until you cease usage of Cytomel and the body recovers. A similar situation occurs when bodybuilders inject testosterone that suppresses natural production of testosterone in their bodies. Effects of Metabolic Activity T3 is a regulator of the oxidative metabolism of energy. When you take liothyronine sodium it will increase the uptake of nutrients into the mitochondria, which raises activity in the oxidative metabolic pathway. This causes everything to work harder within the organism and makes the body demand more fuel. How do I dose my T3? We used to think it was best to take T3-only a good 5-6 times a day. We were wrong. Most report doing much better with just three times day, i.e. they get a better punch than spreading it out more. Some might do three times a day, and reserve a tiny amount at bedtime. Cytomel is not a steroid, but more a of a cutting aid. It’s a synthetic form of the thyroid hormone tri-iodio-thyronine or T3, made up of a metabolite of the amino acid tyrosine and 3 iodine ions. In the body it in turn is made from another hormone, T4, which is secreted by the thyroid under influence of the pituitary hormone TSH (Thyroid stimulating hormone). If a shortage of either TSH or T4 is noted, usually doctors may opt for a replacement therapy. These days the most common prescription is synthetic T4 (synthroid), but in more severe cases of permanent thyroid dysfunction, the choice is given to Cytomel. Simply because T4 is mostly active through its conversion to T3 and T3 is 4-5 times stronger than T4 on a mcg for mcg basis. In bodybuilding circles Cytomel is mostly used as fat-loss drug. Thyroid hormones are often referred to as the metabolic regulators of the body. High levels of T3 speed up the metabolism of an individual, allowing him to burn more calories and use calories more sufficiently. Generally ectopmorphic body-types have very high thyroid levels and in some cases a slight undiagnosed form of hyperthyroidism. Both hyper-and hypothyroidism can have severe consequences on an individual, such as goiters and other nasty stuff, so messing with your thyroid is not something I would advise to beginners. As with insulin, misuse of this compound can leave you dependent on exogenous T3 for the rest of your life (remember Frank Zane?). So some caution and research is required before putting Cytomel in your body. Generally cycles should be limited to 4-6 weeks tops, I recommend 3 and alternating cycles with 3-week cycles of clenbuterol. But most importantly, to avoid a crash or a shock to the thyroid function doses need to be built up over time and tapered off again. More so for cytomel than for any other drug in existence. As far as “when” to take each dose, it’s not rigidly, such as every “four” hours, or every “five hours”. Being rigid like the latter can cause you to take your subsequent T3 too soon (causing an overlap) or too late (which makes you hypothyroid). It’s now more about when your signs (BP, pulse, temps) and symptoms (feeling fatigue, higher heartrate, etc) tell you it’s time to take that second dose, and third dose, etc. That could be mean each dose if anywhere from 3-7 hours apart, depending on those signs and symptoms. If one is doing the early morning T3 circadian dose with T3 (to bring back better adrenal function in the morning), a second and third dose for the day might be 5 mcg each (or 6.25, which is a quarter of a 25 mcg tablet), then raised as needed. Again, the timing is based on when your signs and symptoms tell you it’s time for more. For those simply wanting to start using T3 for their thyroid treatment, they might start on 5 – 15 mcg in the morning, and another 5 – 15 mcg when one’s signs (BP, heartrate, etc) and symptoms (tiredness) dictate it. The spread between the two will be different from individual to individual depending on how fast they metabolize the first dose, so it could be from 3 hours later to 7 hours later. Many dosing schedules based on signs and symptoms seem to fall in the 4-5 hour spread, but again, it’s totally individual. After about five days, a third dose of 5 – 15 mcg is added based on signs and symptoms. Patients seem to do best with three times a day dosing rather than more (though some might add a small amount to bedtime). Each time another amount of T3 is created or added to, patients are looking for either a good reaction (continued good heartrate, blood pressure and temperature), or a bad one–hyper-like symptoms such as high heartrate, BP or temp, which would send the message that one may need to go back down to the previous dose for the time being.